Pharmaceutical Applications

In its directly therapeutic mode, bicarbonate has a long history as an antacid and is frequently the routine agent administered to patients in metabolic-acidosis. The bicarbonate ion is a vital component of human physiology. It helps maintain blood pH; it is the major form of carbon dioxide transport from body tissue to the lungs for exhalation; it is the primary component of duodenal fluid wherein stomach contents are neutralized before entering the intestinal tract; it is a component of saliva where it helps to reduce the attack of orally-generated acids an tooth enamel.

SODIUM BICARBONATE as the active ingredient:
Dosage Form:	Indications:
Sodium Bicarbonate Injection	- Metabolic Acidosis - Barbiturate Poisoning - Salicyclate Poisoning - Methyl Alcohol Poisoning
Sodium Bicarbonate Tablet	- Antacid - Metabolic and Urinary Acidosis
Sodium Bicarbonate, USP Powder	- In solution as an antacid

SODIUM BICARBONATE as one of the active ingredients:

- In solutions and suppositories as a bowel evacuent. - Electrolyte replacement.

SODIUM BICARBONATE as an excipient:

To provide effervescent dose delivery system to help disperse and dissolve the active ingredients.

SODIUM BICARBONATE as an intermediate:

To convert poorly soluble active acid molecules to the more soluble sodium salts.